Search results

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, et al.

Selected by Pierre Caron

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.

Selected by Audrey Noireterre

Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiation

Courtney M. Clark-Hachtel, Jonathan D. Hibshman, Tristan De Buysscher, et al.

Selected by Isabella Cisneros

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by Jessica Chevallier, Pierre Caron

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by Pierre Caron

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

B. van de Kooij, A. Schreuder, R.S. Pavani, et al.

Selected by Jennifer Ann Black

Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers

Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, et al.

Selected by Benjamin Dominik Maier

BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous DNA synthesis

Daniel Salas-Lloret, Néstor García-Rodríguez, Lisanne Giebel, et al.

Selected by Pierre Caron

Nuclear myosin VI maintains replication fork stability

Jie Shi, Kristine Hauschulte, Ivan Mikicic, et al.

Selected by Pierre Caron

Key roles for kinesin-13 and kinesin-20 in malaria parasite proliferation, polarity and transmission revealed by genome-wide functional analysis

Mohammad Zeeshan, Ravish Rashpa, David J Ferguson, et al.

Selected by Jessica Kehrer

RNA targeting with CRISPR-Cas13a facilitates bacteriophage genome engineering

Jingwen Guan, Agnès Oromí-Bosch, Senén D. Mendoza, et al.

Selected by Mandy Neumann

Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases

Eleonora I. Ioannidi, Matthew T. N. Yarnall, Cian Schmitt-Ulms, et al.

Selected by Louise Moyle et al.